Genetically modified tomatoes contain more Vitamin D

Scientists have found a way to edit the genetic makeup of tomatoes to become a robust source of vitamin D.

A research team at the John Innes Centre in Norwich, UK, has been working on the newly designed tomatoes to help people receive appropriate amounts of the vital vitamin.

Vitamin D regulates nutrients like calcium that are imperative to keeping bones, teeth and muscles healthy. Although it is created in our bodies after exposure to sunlight, its major source is food, largely in dairy and meat.

Low vitamin D levels associated with a plethora of conditions from cancer to cardiovascular disease, affect roughly 1 billion people globally, the researchers said.

Tomato leaves naturally contain one of the building blocks of vitamin D3, called 7-DHC. Vitamin D3 is considered best at raising vitamin D levels in the body.

However, the team used the Crispr tool, which is designed to work like a pair of genetic scissors to tweak the plant’s genome such that 7-DHC substantially accumulates in the tomato fruit, as well as the leaves.

When leaves and the sliced fruit were exposed to ultraviolet light for an hour, one tomato contained the equivalent levels of vitamin D as two medium-sized eggs or 28 grams of tuna, the researchers wrote in a paper published in the journal Nature Plants.

Most vitamin D3 supplements come from lanolin, which is extracted from sheep’s wool. Since the sheep stays alive, it works for vegetarians, but not vegans. And common foods with high levels of the vitamin, like eggs and tuna, are not vegan either.

But it could be some time before the gene-edited tomatoes are ready to hit supermarket shelves.

To close the current gap in the intake of vitamin D from dietary sources, two medium sized gene-edited tomatoes should be enough, said the study’s lead author, Jie Li, adding that it is hard to tell a gene-edited tomato apart from a wild tomato. Source

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